DOI: 10.36347/sasjm

Pages: 186-193

Zika virus (ZIKV), a flavivirus known since 1947 and spread by Aedes mosquitoes is an arbovirus responsible of ZIKV infections with normally mild clinical symptoms. It’s only since its outbreak in Brazil from when it is considered as serious problem with public health emergency and international concern; thus it appears to be associated with congenital microcephaly accompanied by grave outcomes. Fortunately, at the end of 2016 the ZIKV epidemic starts to decline, resulting in the end of World Health Organization’s zika virus consideration as a problem of public health emergency. Here, we reviewed the transmission, clinical essentials and prevention of ZIKV infection by highlighting the reason behind of zika decreasing, but also the future perspective regarding vaccine and therapy against this virus.