Background: Acute encephalitides are the most common cause of acute neurological disease in children. This is a potentially devastating neurological syndrome with different etiologies including direct central nervous system infection with different agents most commonly viral and those mediated by immune system. The management has changed dramatically in recent years for several reasons including improved diagnostic and brain imaging techniques, better antiviral and more advanced neurointensive care and rehabilitation. Objective: To observe the presentation, diagnostic approach and management of the children admitted in neuroscience department of Dhaka Shishu Hospital. Method: A retrospective analysis of suspected encephalitis was done from records of discharged patients of the Neurosciences Department at Dhaka Shishu Hospital from January 2011-February 2013. SPSS is used for statistical analysis. Result: This study examined 31 patients (17 boys; 56.5 %, 14 Girls;45.16) with a mean onset age of 5.32 years (range 0.5-12 years).Out of 31 cases of AES, 8 patients (25.81%) were JE and 24 patients (77.42%) were non-JE. Among 31cases AES patients, 8(25.81%) were recovered completely (GOSV) , while 14 (45.16%) cases had neurological sequelae (GOS II –IV) with a wide range of severity varying from mild to severe at the time of discharge, 9(29.03%) patient died in the hospital (GOS I). Conclusion: The majority of cases of encephalitis have no known etiology with HSV being the most commonly identified pathogen in developed countries. Despite treatment with acyclovir, morbidity remains high. Diagnostic criteria, laboratory facility, treatment guideline and long term follow up is essential.

Coronavirus (COVID-19) disease is a highly contagious disease and has a serious psychological impact and mental health problems throughout the entire world. The aim of this study is to find out the Psychological factors which are responsible for the decreasing rate of COVID-19 tests in Bangladesh. A nationwide online survey was conducted during April 2020 to June 2020 by a magazine related to mental health named “Moner Khbor”. Among 560 participants who gave their opinion about the reluctance of testing COVID-19, 65% were male and 35% female. 23.57% participants think that the rate of COVID-19 test is decreasing due to facing lots of troubles and harassments during test procedure. 22.32% participants believed that people lost their credibility per test and 16.07% believed that the risk of infection increases when they go to hospital for a test. Several psychological reasons were found from that survey which is responsible for the decreasing rate of COVID-19 tests in Bangladesh.

Primary intraosseous carcinoma (PIOC) is a rare tumor that has been infrequently reported. Carcinoma arising primarily from the jaw is a locally aggressive lesion with poor prognosis. Primary intraosseous carcinoma (PIOC) lesion develops either de novo remnants of odontogenic epithelium, odontogenic cyst/tumor, epithelium remnants, or/and salivary gland residues. This article describe a case of primary intraosseous carcinoma of mandible.

Introduction: While recent studies are still arguing the efficacy of Hydroxychloroquine and Azithromycin to heal patients with SARS-CoV-2 infection, Moroccan’s ministry of health has decided to maintain the protocol using these drugs. The main objective of this study is to characterize the degree and risk of QT prolongation in patients with COVID-19 in association with their use. Methods: This study is a cohort performed at Mohammed V Military Hospital of Rabat, of patients hospitalized with at least 1 positive COVID-19 nasopharyngeal reverse transcriptase polymerase chain reaction (RT-PCR) test result, and who received 10 day of hydroxychloroquine with 7 days of azithromycin from May9 through May26, 2020. Hydroxychloroquine was given orally at 200 mg TID. Azithromycin was given at a dose of 500 mg the first day followed by 250 mg daily for 6 days. Electrocardiogram was performed before the prescription, 2 days after and at the end of treatment. Results: During this period, 327 ECGs were studied, representing 109 unique patients. Their median age was 30 [25.5-44] years and 100% were male. All patients developed a paucisymptomatic form of the virus. Tisdale score varied between 6 and 8 points (89.9%-10.1%). The difference ΔQTc was significant (p<0.01) from day 0 to 10 with a ΔQTc of 16.15 ms. However, the maximal QTc hadn’t exceed 500 milliseconds. None of the patients developed torsades de pointes or any other ventricular arrhythmias. Conclusion: Moroccan experience can reassure the prescribers on the safety of use of this drug combination in the threatening epidemic context.