The Body Mass Index (BMI) and body weight do not give enough information about a person’s body composition. Measuring the fat free mass gives us the extra information we need. The body composition can be measured in several ways. Unfortunately none of these techniques is a gold standard. That is why different techniques are combined in a full body composition assessment. This study aims to assess the prevalence of overweight, obesity and the fat distribution in medical students. Two hundred (200) preclinical, 100 male and 100 female age matched students (mean 18.93 ± 0.75 years) were included in the study. BMI, waist hip ratio, body fat, skeletal muscle mass and their bodily distribution were recorded by using an electronic body composition analyzer. The subjects were divided into undernourished (UN=BMI<18.5 kg/m2), normal (N=BMI>18.5–22.9 kg/m2), overweight (OW=BMI>23-27.99 kg/m2) and obese (OB=BMI >28 Kgm2) groups based on BMI cut off values for Asians. The data analyzed showed that 32% of the Male (mean BMI = 25.41 ±1.46 kg/m2) 33% of the Female (mean BMI =25.03 ± 1.44 kg/m2) were over weight and 16% of Males (mean BMI =31.08 ±1.91) 8% Females(mean BMI= 30.73 ± 1.66) were obese. The average total body fat in males was 20.75 ± 6.69% and 28.55 ± 5.86% in females. The total body fat was high in obese males and females 26.67±4.37, 36.73 ±0.46% respectively as compared to other groups. The visceral fat was high in obese males (14.40 ± 2, 27%) and whereas obese females had normal levels at (9.5 ± 1.0%). The subcutaneous fat was more in the lower limbs than in the trunk area in both males and females. The skeletal muscle mass was about 34.5 ± 3.44% in males and 26.98 ± 2.55% in females which was slightly less than the recommended values. The leg area had more muscle mass than other areas. The findings clearly indicate increase in total body fat increases with BMI and WHR.

Medicinal products are the prime element in the healthcare and must manufacture with the highest quality, safety & efficacy level. There are multiple principles to obtain such quality are now biggest interest in pharmaceutical industry. One of the important principles that industries follow is Validation. It is the art of designing and practicing the designed steps alongside with the documentation for all processes, methods, computer systems, equipment qualification & revalidation. According to GMP validation studies it is the necessary part of GMP and required to be done as per predefined protocols. Validation master plan (VMP) defines the principles involved in the qualification of a facility, describes the systems to be validated, and provides a updated plan for accomplishing and keeping a qualified facility. The VMP is quite different than validation procedure (SOP), which explains the specific process for performing validation activities.

Introduction: Since its discovery in December 2019 in Wuhan, China, the SARS-CoV-2 virus has rapidly spread the world over. Much research involving the virus, disease and its pathogenesis is now published. However, apart from some case studies, there is no large scale reporting done of the oral findings in patients infected by the virus. Aims: To record the oral soft tissue findings, report significant or peculiar findings, if any, and correlate laboratory and clinical findings, in patients suffering from Covid-19 disease. Methods and material: 101 COVID -19 patients admitted at a tertiary healthcare and medical teaching institute were clinically examined by a trained single investigator (House officer from the department of Dentistry of LTMMC & LTMGH, Sion Mumbai) in September 2020. Results: Thirty-nine patients had oral findings. A majority (twenty-two) had ulcers, seven showed signs of inflammation of their oral mucosa, five had white oral mucosal patches, three had bald tongues, four had angular cheilitis, and two patients had spontaneous bleeding due to oral lesions. Eight patients also had atypical ulcers, mostly on their tongue. These ulcers have, to the best of our knowledge, not yet been reported elsewhere. They could be a manifestation of COVID -19 infections, and the topic of further research. Discussion: COVID-19 patients do exhibit certain oral signs and symptoms, with majority on the tongue.

Introduction: Osteochondroma, otherwise known as osteogenic exostosis, is a benign surface tumor; it develops from an enchondral ossification bone, which and in contact with the epiphysis. Its most dreadful complication is chondrosarcoma. The aim: of our observation is to report a rare and dreadful complication of osteochondroma. Observation: This is an 08 year old female patient, without any particular pathological history, who consulted for a painful swelling of the lower extremity of the left thigh with a chronic evolution. Conclusion: Once the diagnosis of exostosis is made, an annual radiological control is mandatory. Carcinological resection is mandatory as soon as malignant transformation is suspected.