DOI: 10.36347/sjds.2020.v07i10.003

Pages: 156-168

Rare diseases have a prevalence that is not more than 5 cases per 10,000 people. Some rare diseases have oral manifestations. Among these conditions, there are some syndromes, such as Gorlin Goltz, Turner syndrome, SAPHO, Williams syndrome, Schimke Immuno, Cherubism, and Neurofibromatosis type 1. Considering their low incidence and high complexity, these disorders require a diagnostic and therapeutic approach based on the interaction of several specialists. In these field, the dentist plays a leading role: he is at the forefront of the early detection of diseases whose prodromal signs may forerun systemic manifestations by few years. Orthopantomography (OPT) allows to identify changes in bone structures and dental anomalies of shape and number, often associated with the above listed manifestations. The aim of this article is to show how the dentist, basing on some radiological evidences, may be able to make an early diagnosis or to formulate a diagnostic hypothesis that will need to be approved by a multidisciplinary team.