DOI: 10.36347/sjams.2022.v10i11.042

Pages: 2052-2056

Background: Uterine fibroid (UF) is a common tumor of the female reproductive system. Though most of the women with fibroids are asymptomatic, approximately 30% of them can mention about some severe symptoms like abnormal uterine bleeding, pelvic pain, anemia, back pain, urinary frequency and even infertility etc. Generally, among the patients with uterine fibroids, prevalence of vitamin D deficiency is found. But, the impact of vitamin D on reduction of the sizes the uterine fibroids are still unknown. Aim of the study: The aim of this study was to assess the impact of vitamin D supplementation among the women with uterine fibroid in different age groups. Methods: This prospective observational study was conducted in the department of Radiology & Imaging, BSMMU, Dhaka, Bangladesh during the period from January 2020 to December 2020. In total 75 women with uterine fibroid were enrolled in this study as study population. Before data collection proper written consents were taken from all the participants. Along with the data regarding fibroids and vitamin D status, all the demographic and clinical data were collected and analyzed. In data collection, a predesigned questioner was used. All data were processed, analyzed and disseminated by using MS Excel and SPSS version 23.0 program as per necessity. Results: In this study, in assessing the fibroid’s sizes of several age group patients, between baseline and follow-up we found that, at baseline, in 20-30, 31-45 and >45 year’s age groups, the mean ±SD sizes of fibroids were 3.32±0.46, 3.91±0.50 and 4.05±0.51 cm respectively. On the other hand, at follow-up stage in those groups the mean ±SD sizes of fibroids were found as 2.64 ±0.40, 3.66±0.48 and 3.5±0.47 cm respectively. Finally, in evaluating the impact of vitamin D supplementation among our participants, comparing the fibroid sizes between baseline and follow-up stages, we observed that, in >45 years’ age group the fibroid size change was non-significant (P<0.05). ..