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Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 11
Phenytoin Induced Toxic Epidermal Necrolysis Syndrome
Dr. Raghav R Nagpal, Dr. Mitesh Thakkar, Dr. Jaishree Ghanekar
Published: Nov. 7, 2019 | 87 64
DOI: 10.36347/sjams.2019.v07i11.006
Pages: 3518-3520
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Abstract
Steven johnson syndrome (SJS) and Toxic epidermal necrolysis (TENS) are rare but potentially fatal cutaneous hypersensitivity reactions most often triggered idiosyncratically in response to drugs or viral infections. We report a case of TENS syndrome secondary to phenytoin treated with cyclosporine. Various medications have been used previously for its treatment including intravenous immunoglobulin, steroids, cyclosporine, cyclophosphamide, TNF antagonists, pentoxiphylline but overall cyclosporine has shown superior efficacy.