DOI: 10.36347/sjams.2019.v07i11.012

Pages: 3550-3556

Background: Modified ultrafiltration (MUF) after cardiopulmonary bypass (CPB) in children decreases body water, removes inflammatory mediators, improves hemodynamics, and decreases transfusion requirements. The optimal target population for MUF needs to be defined. This prospective, randomized study attempted to identify the best candidates for MUF during operations for congenital heart disease. Objective: To assess the short-term outcome of modified ultrafiltration in pediatric cardiac surgery. Methods: This prospective study was conducted among the Informed consent was obtained from 60 patients with complex congenital heart disease undergoing operations with CPB during January 2014 to June 2019 in Pediatric Cardiac Surgery Department at Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh. They were randomized into a control group (n=30) of conventional ultrafiltration during bypass and an experimental group modified ultrafiltration after bypass (MUF group, n=30). Postoperative arterial oxygenation, duration of ventilatory support, transfusion requirements, hematocrit, chest tube output, and time to chest tube removal were compared between the groups stratified by age and weight, CPB technique, existence of preoperative pulmonary hypertension, and diagnosis.