DOI: 10.36347/sjams.2019.v07i11.037

Pages: 3674-3677

A retrospective study, carried out on 29 patients with Cryptococcus laurentii infection admitted to a tertiary care hospital, during a study period of one year. The demographic profile, clinical presentation, risk factors/predisposing underlying condition responsible for development of the disease and final outcome of these patients were analyzed. In addition MIC of the antifungal drugs against Cryptococcus laurentii isolates was analyzed. It was observed that C.laurentii can involve diverse organ system with varied clinical presentation. Disease can range from a mild localized skin infection to a fulminant septicemia or peritonitis. Debilitated individuals or persons with impaired immunity or with invasive devices are more prone to infection with C laurentii. Antifungals, specifically fluconazole and Amphotericin B remains the mainstay of the treatment, however antifungal resistance should be evaluated for these isolates to avoid the treatment failure.