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Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 11
Role of Adenosine Deaminase and Lymphocyte/Neutrophil Ratio in the Diagnosis of Tuberculous Pleural Effusion in Patients with Exudative Pleural Effusion
Dr. D. Dhanalakshmi, Dr. D. Pallavi Reddy
Published: Nov. 28, 2019 | 47 44
DOI: 10.36347/sjams.2019.v07i11.057
Pages: 3766-3769
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Abstract
Tuberculosis (TB) is one of the most common cause of exudative pleural effusion in India and pleural effusion is the second most common site of extrapulmonary TB after lymph node. Main aim of this study to evaluate the role of ADA and L/N ratio in the diagnosis of tuberculous pleural effusion in patients with exudative pleural effusion. A prospective observational study is done on 120 patients visiting govt chest hospital, hyderabad with exudative pleural effusion age more than 12. Hemodynamically unstable patients were excluded from the study. 84 patients were males and 36 were females. Maximum number of patients was seen in age group 21-30 years. Total ada was found to be >40 u/l in all tubercular effusion with l/n ratio >0.75. When ada> 40U/L is considered alone in diagnosing tubercular effusion the sensitivity, specificity, positive predictive value, and negative predictive values are 100%, 82.6%, 96% and 100% respectively. Combination of ADA along with L/N ratio increased sensitivity and specificity to100% and 91.3%respectively.