DOI: 10.36347/sjams.2019.v07i11.065

Pages: 3800-3803

This prospective study was carried out in Gauhati Medical College and hospital from April 2018 to May 2019. The main aim of the study was to find the prevalence of hypothyroidism, overt hypothyroidism and subclinical hypothyroidism in patients attending antenatal OPD and their fetomaternaloutcomes. The study was done in 400 women with single pregnancy of age 18-35years`with no associated medical illness and no prior history of hypothyroidism with informed consent. Serum TSH was done in first visit and patients with raised TSH were advised fT3, fT4 and anti TPO antibody and were followed up till their delivery. The prevalence of hypothyroidism is high (46.75%). There is significant increase in spontaneous abortion (p=0.013), gestational hypertension (p=0.025), preterm birth (p=0.008) and neonatal jaundice (p=0.039) in hypothyroid cases. There is increased incidence of spontaneous abortion (p=0.009) and still birth (p=0.003) in anti TPO antibody positive cases.