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Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 04
Comparing Echocardiographic Findings with HbA1C, TSH and Lipid Levels in Postmenopausal Women: A Single Centre Study from Gwalior
Dr. Sutakshee Sonwani, Dr. Srishti Sonwani, Dr. O P Jatav
Published: April 30, 2019 | 82 64
DOI: 10.36347/sjams.2019.v07i04.010
Pages: 1416-1419
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Abstract
Background: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in women. Oestrogen deficiency after spontaneous or medically induced menopause is an important risk factor for CVD. Obesity, abnormal lipid profile, hypertension, diabetes mellitus, cigarette smoking, sedentary lifestyle are common risk factors for CVD development. Aims and Objectives: To study the ECHO findings and correlate with symptoms, HbA1c, TSH and lipid levels in postmenopausal women. Materials and Methods: Sixty postmenopausal women (40-50 years) were studied between January 2016 to September 2017 at Department of Medicine, J.A. Group of Hospitals, G.R. Medical College, and Gwalior. Postmenopausal symptoms, age, blood sugar, HbA1C and ECHO were done in all patients. Lipid abnormality and TSH were performed in all subjects. Data were analyzed using IBM SPSS ver. 20 software. P value of <0.05 is considered as significant. Results: Mean age at menopause was 46.7 year. Majority of the women were illiterate and had sedentary life style. Eighteen women were overweight and 4 women were obese. Among the women with Hot Flushes (N=14) and who showed weight gain (N=4), one in each had abnormal ECHO. Majority of the patients had SBP ≤120 mmH (n=59) g and DBP≤80 mmHg (n=59).In patients with HbA1c <6.5, 6.5-8.4 and >8.5%, 1, 0 and 1 patients had abnormal ECHO respectively. In patients with BMI 18.5-24.9, 25-29.9 and >30 kg/m2, 2, 0 and 0 patients had abnormal ECHO respectively. In patients with TG≥150, HDL<50, LDL≥100 and VLDL≥30 mg/dl, 0, 1, 1, 0 and 1 patients had abnormal ECHO respectively. Conclusion: ECHO findings revealed that risk of CVD development may increase among post-menopausal women who were overweight, had hot flushes and abnormal lipid profile.