DOI: 10.36347/sjams.2019.v07i04.034

Pages: 1539-1541

Background: Grave’s disease is one of the causes of hyperthyroidism in paediatric patients presenting with goitre. The disorder is immune mediated which results from production of TSH antibodies by stimulated B lymphocytes. These immunoglobulin bind to TSH receptors and stimulate thyroid growth and thyroid hormone overproduction. Clinical presentation of Paediatric Grave’s disease is enlarged thyroid gland, exophthalmos, tachycardia, tremors, sweating, irritability and weight loss. Thyroid function tests in these cases reveal decreased TSH level and high T3 and T4 levels. Case report: We present a case of Paediatric Graves’ disease in a six year old female patient with thyroid enlargement and complain of palpitation, irritability. Thyroid function tests showed low TSH and high T3 and T4 levels. Cytological examination revealed features of Grave’s disease. Conclusion: Fine needle aspiration cytology plays important role in diagnosis of Paediatric Grave’s disease. It serves as a non-invasive and cost effective diagnostic tool in diagnosis of paediatric thyroid lesions.