DOI: 10.36347/sjams.2019.v07i04.051

Pages: 1618-1620

Background: Thyroid dysfunction is a major public health problem in India. Hypercholesterolemia and raised serum low density lipoprotein (LDL) cholesterol levels have been found to be associated with Thyroid disorders. Thus, altered lipid profile plays a supportive role in diagnosis of thyroid dysfunction. The aim of our study was to find out the variations of thyroid hormones and lipid profile in hyperthyroidism and hypothyroidism in patients admitted at GCS Medical College and Research Institute, Ahmedabad with their clinical implications compared to the published studies so far. Materials and Methods: This was a hospital based prospective cum retrospective study at GCS Medical College and Research Institute, Ahmedabad. The variables collected were age, gender, T4, T3, TSH, fT4, Total Cholesterol, LDL and Triglyceride levels. Descriptive statistics and testing of hypothesis were used for the analysis of data. Results: 150 Patients attending Medicine OPD at GCS Medical College and Research Center, Ahmedabad with abnormal TSH value were included in the present study. The distribution of hypothyroidism and hyperthyroidism were 64% and 36% respectively. There was a positive association between hypothyroidism and TC>200, LDL>130 and TG>200mg/dl; 28.57% of hypothyroid patient had hypercholesterolemia and 21.43% had hypertriglyceridemia. The mean TC, LDL and TG levels were increased progressively with the increase in the serum TSH.