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Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 05
Comparison of Bolus Phenylphrine and Mephentermine for Maintainance of Arterial Blood Pressure during Spinal Anaesthesia in Cesarean Section
Dr. Sumanta Mondal, Dr. Souvik saha
Published: May 22, 2019 | 92 60
DOI: 10.36347/sjams.2019.v07i05.018
Pages: 1775-1780
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Abstract
This prospective randomized study was conducted in 90 singleton pregnant patients scheduled for elective caesarean section who developed hypotension after spinal anaesthesia. They were randomly allocated to Group P-Phenylphrine use (n=45) and Group M-Mephentermine use(n=45) of ASA grade I and II in the age group of 20 -30 years .Both groups were compared with respect of systolic and diastolic blood pressure, heart rate,spo2 and neonatal Apgar score. We conclude that Mephentermine (bolus 3mg/ml) is better than phenylephrine (bolus 50μg/ml) as it was able to sustain a higher rise in systolic blood pressure and bring it to baseline values with fewer repeat dose requirements and fewer incidences of hypotension compared to phenylephrine. But phenylephrine was able to decrease the heart rate back to baseline levels and maintain it at that level, while Mephentermine further raised it. Neonatal Apgar score was same in the two different groups.