DOI: 10.36347/sjams.2019.v07i05.036

Pages: 1870-1875

This was an observational prospective experimental study was distributed in Dhaka Shishu Hospital (DSH) from July 2015 to June 2017. Our aim was to observe echocardiographic findings of Hypoxic Ischemic Encephalopathy (HIE) with cardiac functional status in neonates. A total of 75 cases were selected during the study period. These cases were found to have different stages of Hypoxic Ischemic Encephalopathy. A total of 20 cases were found to be in HIE Stage-I, 24 cases in HIE stage-II and 31 Cases in HIE stage-III. Occurrence of myocardial dysfunction in different stages of HIE. Difference between Stage-I and stage-II was not found significant statistically. Various cardiac changes determined by echocardiography. Common cardiac abnormalities seen were Pulmonary hypertension, Tricuspid regurgitation, right atrial and right ventricular dilatations, left atrial and left ventricular dilatations and myocardial dysfunctional. Occurrence of myocardial dysfunction in different stages of HIE. Myocardial dysfunction was seen mainly in patients with HIE stage-II and stage-III and only one case in Stage-I. For comparison of systolic and diastolic dysfunction in different stage of HIE patients, ANOVA with post hoc multiple comparison analysis test was done. Analysis revealed significant deterioration of myocardial function (except RV diastolic function) between stage-II and stage-III, Stage-III and Stage-I but not between Stage-I and stage-II. Combined ventricular function assessed by myocardial performance index (Tei index) also showed increasing deterioration of myocardial function between stage-II and stage-III, Stage-III and Stage-I, and not between Stage-I and stage-II. Showing association of myocardial dysfunction among the cases with different stages of HIE. Analysis done by Chi squire test revealed that there was significant association myocardial dysfunction with hypoxic ischemic encephalopathy (p-value<.001). Risk estimation of myocardial dysfunction for prolonged hospi