DOI: 10.36347/sjams.2019.v07i05.044

Pages: 1905-1909

To study the effect of altered thyroid hormone (FT3&FT4) and Thyroid Stimulating Hormone (TSH) levels on asphyxia related neonatal mortality.It was a hospital based observational, Analytical study, 32 Term babies with perinatal asphyxia (as per NNF definition) were taken, Thyroid hormones (FT3&FT4) and TSH levels were measured and Outcome results were analysed using student ‘t’ test and Receiver operating characteristic (ROC) curve. P value <0.05 was considered significant. Cases of perinatal asphyxia expired had significant low level of S.FT4 (1.22 + 0.27 ng/dl) as compare to discharged (1.58+ 0.38 ng/dl). Cut off value of S.FT4 ≤ 1.39 ng/dl & S.TSH ≤ 3.8 8uIu/ml combined was having a good predictive value ( SN- 77.2 , SP- 90, PPV- 94.44 & NPV- 64.29) for asphyxia related neonatal mortality.Cut off value of combinedS.FT4 ≤ 1.39 ng/dl & S.TSH ≤ 3.8 8uIu/ml have good predictive value for asphyxia related neonatal mortality.