DOI: 10.36347/sjams.2019.v07i05.070

Pages: 2041-2044

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder and is the leading cause of hyperandrogenemia in women. Acne vulgaris is also a common cutaneous manifestation of hyperandrogenism. We conducted a cross-sectional study in the department of Dermatology, Community Based Medical College Bangladesh (CBMCB), Mymensingh, Bangladesh during the period from January 2018 to December 2018. Our aim was to determine the prevalence of PCOS in patients with acne and its associated factors with regard to the clinical and paraclinical findings. During study period, a total of 1612 patients were admitted in the hospital. Among them 102 patients were with Acne with a prevalence rate of 6.32%. Among acne group 83 (82%) were women and 19 were male. A total of 83 women, 54(65.06) suffered with polycystic ovary syndrome (PCOS) disorder and 19(34.94) without polycystic ovary syndrome (non-PCOS) disorder were included in the study. So, eighty three (83) women patients with acne were selected in the study as study subjects. A clinical examination was followed by a laboratory examination, including hormone profile and ovarian sonography. Confirmation of Pnon-COS was based on the diagnostic criteria of the National Institute of Health (NIH) and the sonographic findings. The subjects were 16-39 years old. PCOS was diagnosed in 41 (49.39%) patients by sonography methods, while, 54(65.06%) patients were diagnosed as PCOS cases based on the NIH criteria. In this study obesity was 25.27% in the PCOS group and in 27.85% in the non-PCOS group. The prevalence of hirsutism was also bit similar among women with and without PCOS (58.53% vs. 55.73%). Menstrual disturbance was seen higher in women with PCOS (71.52%), which was statistically significant (p=0.001) PCOS versus non-PCOS had profiles of prolactin (20.86±10.50 ng/ml vs. 18.75±8.65 ng/ml), testosterone (0.82±0.55 pg/ml) vs (0.99±0.99pg/ml), dehydroepiandrosterone levels (2.84±2.12µg/dl vs. 1.99±1.25) and which were not statis