DOI: 10.36347/sjams.2019.v07i06.003

Pages: 2056-2060

Abnormalities in hematological indices are frequently encountered in cirrhosis of liver. Multiple causes are contributing to the occurrence of hematological abnormalities. Recent studies suggest that the presence of hematological cytopenias is associated with a poor prognosis in cirrhosis. This study was conducted on 43 patients with chronic liver disease to assess the hematological abnormalities. We found 37(90%) patients had hemoglobin <12gm/dl. Macrocytic anemia was predominant type followed by normocytic normochromic and microcytic type. 24 patients had platelets <1.5lakh /dl. 28 patients had prolonged prothrombin time and INR was raised in 38 patients. 12 patients showed peripheral smear picture suggestive of pancytopenia. We observed patients with anemia had MELD score above 15% compared to patients without anemia. We also observed patients with MELD score above 20% had mean platelets of 1.5l/dl compared to lower score. 38 patients had splenomegaly. We also observed mean platelet count in patient with hepatic encephalopathy was low and prolonged prothrombin time.