DOI: 10.36347/sjams.2019.v07i06.035

Pages: 2207-2215

This work was carried out to investigate the changes in haematological and some physiological parameters among patients who diagnosis with symptoms related to spotted fever in El-Beida City, Libya. This study carried out in the 7 consecutive months (May-November 2018). Over all total number 129 were divided into two groups (adults and children), number 61 males and 30 females for adult, while children's number was 22 males and 16 female. From all patients, blood samples have been taking for multiple tests (these tests including complete blood count, liver function and kidney function). RBC count was statistically different compared to control group in children and adults subjects. Most RBC parameters including were significantly decreased in patients (adults and children/ male and female) compared to control subjects. Only level of mean corpuscular hemoglobin concentration (MCHC) was significantly increased in all patients. Results of WBC were in normal range for couple genders increased slightly without significantly changes except on percentage of lymphocytes that increased in adult’s patients not in children. Results of platelets including mean platelets number (PLT), the volume occupied by platelets in the blood (PCT) and mean platelet volume (MPV) were significantly decreased in both female and male (adults and children). Mean levels of enzymes of liver in the serum of the female and male (adults and children) were significantly increased in patient’s subjects. Kidney function parameters (creatinine and urea) were found more variable in children than in adults in term of statistically significant. Similar pattern of changable were noticed with the mean concentration of sodium, potassium, and chloride (children was more significantly than adults). The predisposing factors for severity were young age. Understanding these haematological/biochemical test are very helpful. Because, early clinical presentations of spotted fever infection include fever, headache