DOI: 10.36347/sajp

Pages: 94-100

The goal of that study was to test the antibacterial activity of the different extracts of Vitexdoniana on three strains of the Staphylococcus aureus: S. aureus Meti-S, S. aureus Meti-R and S. aureus ATCC 25923. Two methods have been used: they are agar well diffusion and the macrodilution method in liquid medium (macrobroth dilution method). Among all the tested strains, ethanolic 70 %, methanolic and ethyl acetate extracts have given the inhibition diameters included between 11 and 26 mm whereas the aqueous extract has only been active on S. aureus Meti-S with an inhibition diameter of 17 mm. The values obtained with the Minimum Inhibitory Concentration of (MIC) are between 0.39 and 53.57 mg/mL and those of Minimum Bactericidal Concentration (MBC) are between 0.39 and 107.14 mg/mL. Moreover, the ethyl acetate extract has shown the best activity against all the tested strains with 3.12, 0.39 and 3.12 mg/mL as MBC respectively on S. aureus Meti-R, S. aureus Meti-S and S. aureus ATCC 25923