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Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 07
Clinicopathological Study of Necrotizing Fasciitis with Special Reference to Fournier’s Gangrene: An Observational Study in a Tertiary Care Hospital, Eastern India
Dr. Pranaya Kunal, Dr. Sushant Kumar, Dr. Ahsan Ulla
Published: July 15, 2019 | 83 65
DOI: 10.36347/sjams.2019.v07i07.008
Pages: 2301-2306
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Abstract
Background: Fournier’s gangrene is an acute, rapidly progressive, and potentially fatal, infective necrotizing fasciitis affecting the external genitalia, perineal or perianal regions, which commonly affect men, but can also occur in women and children. There has been an increase in number of cases in recent times. Despite advanced management mortality is still high and averages 20–30%. Materials & Patients: The present study was a hospital based prospective observational study conducted in the Department of Surgery, MGM Medical College and LSK Hospital, Kishanganj, Bihar. Over the period of two years, 50 cases of necrotizing fasciitis including Fournier’s gangrene have been studied. Of these 50 cases, 12 cases presented in the emergency with local erythema and swelling with severe disproportionate pain to local signs and three with features of shock in addition to above symptoms. Culture and sensitivity test for pus and necroses tissue from the lesions of all patients were evaluated for aetiological organisms. Tissue biopsy was done for definitive diagnosis and also identify others concomitant pathological lesion, if any, necrosed tissue with healthy margin from the lesions of all 50 patients were evaluated. Results: The disease was most common between the aged 30 years and 60 years. The youngest patient in this series was 22 years old and the older years old. 38 patients were males and the remaining 12 were females, giving a female ratio of 3.17:1. Diabetes mellitus the most common pre-existing medical conditions in association with necrotizing fasciitis comprising 42% (total 21 cases) of which diabetes with peripheral vascular disease, diabetes with renal failure and diabetes with tuberculosis is accounts for 2% (1 case) for each respectively. Total number of tuberculosis is found in this study are 4 % (2). Between 21 cases of diabetes mellitus 16 are male (32%) and 5 are female (10%). Idiopathic factor is the most common predisposing factor and is account for 48