DOI: 10.36347/sjams.2019.v07i07.032

Pages: 2437-2440

High levels of acute phase proteins like C-reactive protein are associated with inflammatory reaction or tissue damage. Aim: The present study was conducted in order to identify the levels of serum C reactive protein in patients with acute ischemic stroke. Methods: This prospective cross-sectional study was done in the department of general medicine, Prathima Institute of Medical Sciences, Nagunoor, Karimnagar. A total of n=54 patients were selected out of which n=34 were male and n=20 were female patients. A detailed history was obtained and complete clinical examination including neurological assessment was done. All the patients in the study were > 18 years of age. They were subjected to CT and MRI scan and ischemic stroke were confirmed. The biochemical investigation for serum hs-CRP was determined. Results: The mean hs-CRP levels in ischemic stroke patients were found to be 6.97 ± 3.25 mg/L. The comparison of the mean hs-CRP levels based on gender was done a value of hs-CRP less than 3.0 mg/L was considered as normal and the values of hs-CRP > 3.0 mg/L were considered increased. Out of 34 male patients in n=23 (67.65%), the values of hs-CRP were found to be increased similarly in n=12 (60%) females the values were also found to be increased. Conclusion: men are at a greater risk of stroke at an early age as compared to female counterparts. And the hs-CRP levels are positively correlated with stroke and modified Rankin Scale. Higher CRP clearly indicates greater severity of the stroke and poor prognosis.