DOI: 10.36347/sjams.2019.v07i07.038

Pages: 2471-2475

We carried out a comparative study in the department of surgery, 250 Bedded General Hospital, Pabna, Bangladesh during the period from January, 2015 to June 2018. A total of 160 patients who were admitted for elective general surgical operations were selected by purposive sampling. Out of these 65 patients were given 3 dose of prophylactic antibiotic and another 95 patients were given 7 days of traditional prophylactic antibiotic. Evidence of surgical site infection was observed in both groups up-to 30 days postoperatively in inpatient and outpatient. Our aim was to compare the result of short-term three prophylactic antibiotic versus traditional long-term seven days prophylactic antibiotic for prevention of surgical site infection. The age distribution of the patients. 17(10.7%) were below 20 years of age. Nearly 20% of patients were between 20-30 years of age, followed by 18.2% between 30-40 years, 25.2% between 40-50 years and the rest 27% were 50 years above. The comparison of sex distribution between 2 antibiotic regimens. About 50% of the short-term antibiotic group and 64.6% of the long-term antibiotic group were male and the male female ratio was roughly 3:2. In short-term group (9.23%) and in long-term group (7.36%) got surgical site infection. The difference in infection rates between two groups was not statistically significant. (P-value =0.771). The short-term regimen is less costly for the patients, has the same prophylactic benefits. There is no advantage in prolonging a patient’s hospital stay following elective surgery to administer postoperative antibiotics for long duration. This study conclude that short-term prophylactic antibiotic is as effective as traditional long-term prophylactic antibiotic for prevention of surgical site infection and it is cost effective.