DOI: 10.36347/sjams.2019.v07i07.041

Pages: 2485-2490

Antibiotic prophylaxis for surgery has appeared indicated whenever likelihood of infection is great or consequences of such are catastrophic. Surgical site infections are associated with prolonged hospital stay and increase costs of treatment. The majority of surgical site infections have been linked to the failure to administer prophylactic antibiotics or the inappropriate timing of antibiotic prophylaxis. We carried out a comparative study in the department of surgery Rajshahi Medical College Hospital, Rajshahi, Bangladesh during the period from July 1, 2007 to June 30, 2008. A total of 160 patients who were admitted for elective general surgical operations were selected by purposive sampling. Among them 65 patients were given 3 dose of prophylactic antibiotic and another 95 patients were given 7 days of traditional prophylactic antibiotic. Evidence of surgical site infection was observed in both groups up-to 30 days postoperatively in inpatient and outpatient. Our aim was to compare the result of short-term three prophylactic antibiotics versus traditional long-term seven days prophylactic antibiotic for prevention of surgical site infection. In short-term group (9.23%) and in long-term group (7.36%) got surgical site infection. The difference in infection rates between two groups was not statistically significant. (P-value =0.771). Short-term prophylactic antibiotic can be recommended in elective surgical as it is less costly and has the same prophylactic benefits as that of traditional long-term prophylactic antibiotic.