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Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 07
A Study of Platelet Parameter as a Diagnostic and Predictive Biomarker for Preeclampsia
Dr. Krishna Kant Shiromani, Dr. Sandeep Barve, Dr. Usha Amliyar
Published: July 30, 2019 | 54 55
DOI: 10.36347/sjams.2019.v07i07.042
Pages: 2491-2494
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Abstract
Background: Preeclampsia is one of the major health problems during pregnancy. It complicates 3%–8% of pregnancies and causes marked increase in perinatal, maternal morbidity, and mortality, Although the exact pathophysiology of preeclampsia is not completely understood. Objective: The Objective of the study is to measure platelet count(PC), mean platelet volume(MPV) and platelet distribution width(PDW) in preeclampsia patients and compared its results with normal pregnant females to diagnose and assess the severity of preeclampsia. Methodology: A Retrospective study of sixty preeclamptic women were the cases and an equal number of healthy pregnant women were the controls of 28-32 weeks of gestation of age group 25-35 year. Preeclamptic patients were separated into three groups as mild (30), moderate (15) and severe preeclampsia (15).Platelet count, mean platelet volume and platelet distribution width was measured from all participants and results between preeclamptic and normal pregnant women were compared by calculating p value by using online student t test calculator.p value less than 0.01 was considered as a difference of significance. Results: The mean concentration of platelet in preeclampsia group is 1.705±.60000 as compared to 2.60 ±65000 in control group. The mean concentration of Mean platelet volume (fl) platelet in preeclampsia group is 9.408±1.30 as compared to 9.120 ±0.98 in control group. The mean concentration of platelet distribution width in preeclampsia group is 15.56±2.56 as compared to 10.58 ± 1.52 in control group. Conclusion: The present study revealed that low platelet count is associated with preeclampsia and eclampsia. The estimation of platelet indices can be considered as early, economical and rapid procedures of assessment of severity of PIH cases. Clinically platelet indices can be a useful screening test for early identification of preeclampsia and eclampsia. Also platelet indices can assess the prognosis of this disease in pregnant