DOI: 10.36347/sjams.2019.v07i07.046

Pages: 2504-2507

Objectives: Diabetes is a metabolic disease which hosts plethora of disease conditions. Among which is hypertension is the key initiating the cascade of metabolic derangements. Blood pressure impairs the metabolic functions and even leads to inviting high free radicals (reactive species). Alongside, increase in psyhchological stress occurs too aggravating the situation which may be borne out of diabetic conditions or others environmental elements. Methods: We collected blood samples from 100 diabetic patients and 50 controls. Serum levels of malondialdehyde and cortisol were measured by ultraviolet spectrophotometry and enzyme-linked immunosorbent assay kit, respectively. Results: We found serum total-antioxidant, malondialdehyde and cortisol levels of both the hypertensive and normotensive diabetes patients significantly higher than their healthy counter parts. Conclusion: The present study showed that increased serum levels of malondialdehyde and cortisol are strongly associated with diabetes but not with each other. Therefore, we believe elevations of malondialdehyde and cortisol in serum level arise independently and they could serve as biomarkers for diabetic patients.