DOI: 10.36347/sjams.2019.v07i07.047

Pages: 2508-2512

Introduction: Besides non-infectious diseases and disorders, infectious diseases still remain a major cause of morbidity and mortality in third-world countries including Bangladesh. Bacterial pathogens resistant commonly used antimicrobials are now creating a challenge to the clinicians and researchers. Methods: It was a prospective study carried out during the period from January 2014 to October 2014 in Rajshahi Medical College Hospital, Bangladesh. Samples were collected from both sexes and different age groups admitted in the mentioned hospital. The clinical isolates were tested and the included specimens were Urine, Pus, Sputum, Vaginal swab, Throat swab and Conjunctival swab. Result: In this study the selected antibiotics were Imipenem and it was 97.32%. Then Ceftriaxone 90.64%, Cefixim 89.76%, Cefuroxim 90.85%, Ofloxacin 87.82%, Cephradin 85.76, Amoxyclav 86.27, Ceftazidim 83.14%, Levofloxacin 83.13%, Nitrofurantoin 82.50%, Azithromycin 82.10%, Fusidic Acid 80.04%, Vancomycin 79.23%, Ciprofloxacin 77.04%, Mecillinam 74.18%, Cotrimoxazole 74.40%, Gentamycin 73.72 and Amikacin 72.81%. On the other hand, the main pathogenic bacteria we found were Escherichia coli, Klebsiella species, Staphylococus aureus, Pseudomonas species, Provindencia species and some other species with little effect. Out of total organisms isolated, majority were Escherichia coli & Klebsiella species. On the other hand, among 18 antimicrobials we found Imipenem as the most effective against the pathogens. Conclusion: Day by day multi drug resistance patients are increasing. In our study we also found some broad spectrum antibiotics less effective in some cases which is very alarming. We would like to recommend for conducting more and multi-centered study to collect more and specific information about common and notorious pathogenic bacteria and antibiotics against them.