DOI: 10.36347/sjams.2019.v07i07.048

Pages: 2513-2520

Autism is a pervasive developmental disorder characterized by qualitative impairments in social interaction and communication, and stereotyped repetitive behavior. A better understanding of autism not only holds promise for earlier intervention and prevention, but will also yield important insights about both pathological and normal development. Determining the epidemiology of autism is likely to help in understanding this puzzling disorder. Current study aimed at determining the risk factors of autism among children of age 4 to 18 years for care of autistic child at Dhaka metropolitan city and SSMC & Mitford Hospital. The study adopted Case control setting, including one government and one private organization involving in the field with. Forty five cases of autism were selected from the two centers. Controls were selected matching for age and sex and place of residence to cases. Regarding Socioeconomic status based on family income the group dosent differ statistically. Specific co-morbidity among mothers during pregnancy like fever, Psychiatric disorder, diabetes, hypertension and cardiac disease were found to be similar in both the groups. Drug use during pregnancy is also not found to exert in the current study, however inquiry about the effect of individual drug is not tested excepting for antipsychotic drug. Birth-order, presentation at births either vertex or breach does not alter the risk of childhood autism. Mode of delivery, particularly, cesarean section over normal vaginal delivery and Gestational age at birth particularly preterm rise the risk of Development of autism. However in multivariate analysis adjusting for other factors these risks was found to be not significant. Child factors were also investigated, particularly the events since birth. None of birth weight, requirement of parinatal resuscitation immediately after birth, History of breast feeding and most importantly the immunization history didn’t show any increased risk. In present study m