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Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 07
Effect of Obesity on Androgen Levels Among Diabetic Patients
Satish Chaudhary, Ritin Sharma, Madan Kaushik, Roshan lal
Published: July 30, 2019 | 45 58
DOI: 10.36347/sjams.2019.v07i07.053
Pages: 2540-2543
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Abstract
Aims: To study BMI and testosterone levels in men with type 2 diabetes mellitus. Material and Methods: An observational, cross sectional study was performed in 193 male type 2 diabetic patients. Height and weight were evaluated in all subjects. BMI was calculated as weight (kg) divided by square of height (m2) and was expressed in kg/m2. Classification of BMI was done according to western pacific regional office (WPRO) (2000) guidelines for BMI for Asian population. Total Testosterone Levels and Free Testosterone Levels were measured based on chemilumiscence on Beckman coulter access 2 immunoassay system (time for collection of samples was between 7am to 11am). Observations: The average age of study population was 43.32 ± 5.10 years. A total of 142 (73.57%) patients were known cases of diabetes mellitus. A total of 51 (26.42%) patients were newly diagnosed Type 2 Diabetes Mellitus. Average Body Mass Index (BMI) of the patients was 25.73±3.33 kg/m.2. out of 193 patients, total number of Obese II ( BMI ≥30) patients were 33 (17.09%), Obese I ( BMI 25-29.9) were 62 (32.12%), overweight at risk ( BMI 23-24.9) were 60 (31.08%) and normal (BMI 18.5-22.9) were 37 (19.17%). OUT of 33 Obese II (BMI ≥30) patients, 21(63.63%) patients were having low total testosterone levels and 12 (36.36%) were having normal total testosterone levels. Conclusion: 63.63% of obese diabetic men aged between 30 to 50 years have low total testosterone levels and 48.48 % of obese patients have low free testosterone levels. Obese diabetic patients have low total testosterone levels as compared to non-obese diabetic patients which conclude that obesity also leads to low testosterone levels in addition to diabetes, which associated with additional increase in low testosterone levels.