DOI: 10.36347/sajp

Pages: 125-129

The plant Pergularia daemia (Asclepiadaceae) is traditionally used as a medicinal agent and they are widely distributed to tropical and subtropical region of India. Therefore, the present work has been designed to evaluate antioxidant and cytotoxicity potential of Pergularia daemia so as to claim folklore uses of P. daemia. The in vitro antioxidant activity was studied using DPPH Scavenging, Nitric Oxide Scavenging and β-carotene-linoleate scavenging model and cytotoxic activity of AEPD was studied by the MTT assay using using A-549 (Human, Lung Carcinoma) HT- 29 (Colon Carcinoma) cell lines. AEPD was studied at different concentrations, in which it showed a moderate to potent activity which confirms that it is having cytotoxic activity. AEPD was also studied for its in vitro antioxidant property by different methods. AEPD has a hydrogen donating property, which may be attribute to the good antioxidant activity. The in vitro data suggest that the extract is having both the in vitro antioxidant and cytotoxicity activity