DOI: 10.36347/sjams.2019.v07i07.062

Pages: 2682-2585

Introduction: Calcium channel blockers are proposed to play a vital role for the management and control of hypertension. Dihydropyridine-type calcium channel blockers like Amlodipine are frequently used because for their strong antihypertensive and minimal adverse side effects. However, it is commonly associated with the causation of pedal edema among the patients. Cilnidipine, another novel new generation calcium channel blocker is presumed to cause lesser pedal edema with a satisfactory clinical control of hypertension along with negligible side effects. Objective: The main objective of this study was to compare between the efficacies of Amlodipine Cilnidipine in treating the hypertensive patients. Methods: This comparative study was conducted in the Department of Cardiology, Rajshahi Medical College Hospital, Rajshahi, Bangladesh during the period from January 2018 to December 2018. The present study included assessment of 80 hypertensive patients that were undergoing treatment for the same. Auscultatory method with standard mercury sphygmomanometer was used for the measurement of the blood pressure. All the 90 patients were divided into two study groups with 40 patients in each group. The first group comprised of patients who were prescribed amlodipine 5–10 mg/day while the other group included patients who were given cilnidipine 10–20 mg/day orally as a treatment protocol for hypertension. The mean values of Systolic blood pressure and Diastolic blood pressure during check-up were recorded and assessed. All the results were analyzed by SPSS software. Results: The mean SBP in the Amlodipine group patients and cilnidipine group patients was 139.1 and 144.2 mm of mercury respectively. The mean DBP in the Amlodipine group patients and in the cilnidipine group patients was 80.2 and 85.3 mm of mercury respectively. Non-significant results were obtained while comparing the mean SBO and DBP among patients of the two study groups. 28 patients in amlodipine group and 5 p