DOI: 10.36347/sjams.2019.v07i07.072

Pages: 2623-2626

Atrial fibrillation is the most commonly encountered arrhythmia in cardiological practice, its predominant form in developed countries is non-valvular atrial fibrillation which constantly increasing even in developing countries, further its thromboembolic complications this arrhythmias is associated with a higher risk of mortality, heart failure, and hospitalization. The aim of this study was to assess the epidemiological profile of non-valvular atrial fibrillation (AF) in Bangladesh, to evaluate the therapeutic management and to investigate the part of the different risk factors for embolic events in our local context. This was an observational study on 163 patients admitted for non-valvular atrial fibrillation was conducted in the department of cardiology, Rajshahi medical college hospital during the period from January 2017 to December 2018. All patients underwent electrocardiogram, echocardiography and biological determination of thyroid hormones and renal function their clinical characteristics as well as echocardiographic and therapeutic data were collected and analyzed. The mean age of our patients was 62±11 years with a male female ratio of 1.96:1. Atrial fibrillation was permanent in 63% of patients, paroxysmal in 23% and persistent in 11% of cases. The mean diameter of the left atrium was 44±8 mm with a mean surface area of 25±7 cm2, the average ejection fraction was 51±12%. The most common symptoms were palpitations, dyspnoea and systemic embolism. The average CHA2DS2Vasc score was of 2.49. Among the different embolic risk factors studied, only age diabetes and hypertension were significantly associated with the occurrence of a thromboembolic accident in our study. The epidemiological profile and clinical features of non-valvular atrial fibrillation are different in our local context; an under-utilization of anticoagulant therapy in eligible patients is noted as well as a less frequent use of a rhythm control strategy compared to a rate control strategy.