DOI: 10.36347/sjams.2019.v07i08.015

Pages: 2700-2703

This was a cross sectional study which has been done with a view to compare the clinical and biochemical profile of end stage renal disease (ESRD) population or CKD stage V who are not on any renal replacement therapy with the patients of chronic kidney disease (CKD) stage II and III. This study was carried out on all CKD patients who attended the outpatient department and was admitted, transferred or referred to nephrology department of Sir Salimullah Medical College and Mitford Hospital, Dhaka during the study period. All patients were included in the period from July 2008 to December 2009. Data were collected by using an interviewed questionnaire, examination and investigations. Eighty (80) CKD stage V patients were taken in a group I against 40 cases of CKD stage II and III in group II. Anemia was found in both the group but more severe in the group I. Mean serum hemoglobin level of the group I was 8.327 gm/dl and 10.933 gm/dl in the group II. Edema was present in 46% of patients of group I and in 15% in group II. CKD stage V patients had a mean systolic blood pressure (BP) of 145.6 mm Hg whereas it was 143.6 mm Hg in CKD stage II-III patients. Mean diastolic pressure in group I was 87.81 mmHg which was 82.77 mmHg in group II. Diastolic pressure was more significantly raised in group I patients than the group II. Serum albumin level showed hypoalbuminemia in patients with CKD stage V. It was 2.816 gm/dl in the group I whereas 5.20 gm/dl in group II. From this study we could observe that the clinical and biochemical profiles related to kidney failure were present in more severe form in the patients with non-dialytic CKD stage V patients then the earlier stages (stage II and III) of CKD patients.