DOI: 10.36347/sjams.2019.v07i08.028

Pages: 2763-2766

Organophosphorus is one of the most common compounds incriminated in poisoning in the world, particularly in the developing world. This is a prospective study to look at the ECG changes in patients with OP poisoning and to determine whether it helps in prognostication of the outcome. We conducted a prospective study to look into the ECG changes in patients who presented with acute organophosphorus poisoning to determine the most common ECG changes stratified as per severity and to study if ECG changes can be used to assess the outcome. A total of 50 study patients with a history of acute organophosphorus poisoning were included and ECG changes were noted on admission. The primary end points being death and respiratory failure and secondary endpoint were the length of ICU stay. The most common ECG abnormality seen was ST elevation (32%) followed by Sinus tachycardia (30%),Q-T prolongation (24%) and sinus bradycardia (20%). 91.66% (p 0.023) of the patients who had QT prolongation developed respiratory failure requiring mechanical ventilation and 5 of 12 (41.6%) p 0.02 patients with QT prolongation died. ST elevation, in spite of being associated with mortality and respiratory failure, was not statistically significant. ECG changes can be used to prognosticate patient with acute OP poisoning. QT prolongation was seen to be associated with increased mortality and severity of OP poisoning. It was also noted to have an association with increased length of ICU stay in this study.