DOI: 10.36347/sjams.2019.v07i08.037

Pages: 2812-2814

Objectives: This study was conducted to know the microbial pattern in acute exacerbation of chronic obstructive pulmonary disease patients and impact of BODE index in predicting prognosis and outcome in acute exacerbation of chronic obstructive pulmonary disease patients. Methods: We studied 138 patients of in acute exacerbation of chronic obstructive pulmonary disease admitted to medical ward of DM WIMS Medical College, Meppadi, Wayanad district, Kerala. All patients underwent thorough clinical examination including measurement of SPO2 and FEV1. Relevant Biochemical and microbiological tests were conducted. Patients were classified according to BODE index. Results: Out of 138 patients 88(63.7%) were males and 50(36.23%) were females. Mean age of patients: 52.81 ± 13.6 years. Smoking and exposure to biomass fuels were noted in patients. Microbial isolation was positive in 68.60% of patients. Pseudomonas species were isolated in most of the patients. Many patients were in BODE index -2 category. Most of the deaths were noted in BODE index- 3 category. Conclusion: Microbial data is very limited in acute exacerbation of chronic obstructive pulmonary disease patients. Early antibiotics usage according to culture report improves the outcome of acute exacerbation of chronic obstructive pulmonary disease patients. We need larger randomised studies to assess the microbial pattern and BODE index in acute exacerbation of chronic obstructive pulmonary disease patients.