DOI: 10.36347/sjams.2019.v07i09.023

Pages: 3022-3027

Little is known about the epidemiological character of Acute Kidney Injury (AKI) from North East part of India so this study was carried out to know the epidemiology, clinical characteristics, aetiologies, severity and outcome of the AKI patients. This prospective observational study was conducted at Regional institute of Medical Sciences (RIMS) Hospital, Imphal during September 2015 to August 2017 among the patients admitted with AKI or who developed AKI in-patient in any ward of RIMS Hospital. Patients of 18 years and above, regardless of gender were included in the study. During the study period a total of 304 patients with AKI were found with an incidence of 1.9 % with a male to female ratio of 1.7:1. Mean age of patient was 44.68±13.13 years and the most common age group was 41-50 years (33.5%) in both the sexes. 46.7% of the patient had associated co-morbidities and the most common cause of AKI was sepsis (38.2%). Drugs induced AKI also was common (15.8%) and anti-retroviral therapy (ART) drugs and amino glycoside, were some of offending agents. Intrinsic renal injury was the most common mode of renal injury comprising around 63.2% of the total AKI (p<0.001). Based on the RIFLE criteria 42.1% patient landed in Injury (I) category which was closely followed by Failure (F) and Risk(R). Of the total admitted, 21.7% required dialysis while 17.1% expired during the course of illness. 52.6% of the patient recovered completely (<0.001) whereas 30.56% had partial recovery.