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Scholars Academic Journal of Pharmacy | Volume-2 | Issue-03
Phytochemical analysis and Cytotoxicity studies of Bryophyllum calycium in BHK-21 cells A.
Joshi A, Chauhan RS
Published: March 30, 2013 |
79
58
DOI: 10.36347/sajp
Pages: 190-194
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Abstract
Bryophyllum calycium is a common medicinal plant used in traditional medicine of India founded in the
region of Uttarakhand near Nainital, for curing various infections, bowel diseases, healing wounds and other ailments.
However, its anticancer properties are poorly defined so this was done to extract its anticancer property against BHK-21
cells. This study is a step towards evaluation of the plant against cancer. Methanolic, ethanolic and aqueous extract of the
leaves of Bryophyllum calycium were screened for their anticancer properties. The cells were seeded with all the extracts
and then allowed to grow for 24hrs, the cell growth was inhibited and rounding and clumping of cells were observed
within 24hrs. Ethanolic and Aqueous extracts showed better response then that of its methanolic extract. The
concentration of 10 mg/ml of ethanolic extract inhibited the cancerous growth with high affinity. The extracts inhibited
the growth of the cancerous cell lines