DOI: 10.36347/sajp

Pages: 190-194

Bryophyllum calycium is a common medicinal plant used in traditional medicine of India founded in the region of Uttarakhand near Nainital, for curing various infections, bowel diseases, healing wounds and other ailments. However, its anticancer properties are poorly defined so this was done to extract its anticancer property against BHK-21 cells. This study is a step towards evaluation of the plant against cancer. Methanolic, ethanolic and aqueous extract of the leaves of Bryophyllum calycium were screened for their anticancer properties. The cells were seeded with all the extracts and then allowed to grow for 24hrs, the cell growth was inhibited and rounding and clumping of cells were observed within 24hrs. Ethanolic and Aqueous extracts showed better response then that of its methanolic extract. The concentration of 10 mg/ml of ethanolic extract inhibited the cancerous growth with high affinity. The extracts inhibited the growth of the cancerous cell lines