DOI: 10.36347/sjams.2019.v07i09.055

Pages: 3192-3195

Objective: This study was performed to determine the correlation between serum magnesium (Mg) with Carotid Intima Medial Thickness in CKD Patients on Maintenance Hemodialvsis. Material & Method: This is hospital-based cross-sectional observational study was conducted at the Department of Medicine, Hamidia Hospital and Gandhi Medical College, Bhopal. Fifty patients with end-stage kidney disease on MHD treatment (29 males and 21 females) were studied. After overnight fasting, blood samples was drawn for complete hemogram, blood urea, serum creatinine, lipid profile and serum Mg. Carotid intima media thickness was measured by B mode ultrasound using a 75MHz transducer and was defined as distance between leading edge of first echogenic line (Lumen - Intima Interface) and second echogenic line (Media - Adventitia interface) of far wall. Results: Serum magnesium correlated significantly with mean CIMT (p<0.001). Serum magnesium in CKD patients significantly correlated with Age (P<0.001), sytolic blood pressure (P<0.001), serum Triglyceride levels (P=0.029), PBS (p=0.04) and Mean CIMT (p< 0.01) Conclusion: Our study supports the evidence for the possibility that low magnesium levels are associated with vascular calcification. Also suggest that long-term intervention with magnesium in dialysis patients may retard arterial calcification.