DOI: 10.36347/sjams.2019.v07i09.056

Pages: 3196-3199

Background: Comparison of Effects of Different Treatment Modalities for Diabetic Pregnant Patients on Neonatal Complications. Patients and Methods: observational study among 160 antenatal type2-DM patients attending obstetrics department in lok-nayak hospital, Delhi from 2016-18 and their effects on neonatal complications. Results & Discussion: DM in pregnancy is associated with higher rates of poor foetal, maternal and perinatal outcomes. In women on Metformin, 19/80 (23.75%) women delivered newborns with birth weight appropriate for gestational age (AGA), none of the delivered newborns were SGA (small for gestational age) and 3/80 (3.75%) delivered newborns with birth weight LGA (large for gestational age). In women on Insulin, 3/80 (3.75%) women delivered newborns with birth weight AGA, none of the delivered newborns were SGA and 1/80(1.25%) delivered newborns with birth weight LGA. In women on Metformin + Insulin, 1/80 (1.25%) women delivered newborns with birth weight AGA, none of the delivered newborns were SGA and 2/80 (2.50%) delivered newborns with birth weight LGA. In both case and control groups, all newborns had APGAR score >7 at 5 minutes after birth, none of the newborns was admitted in NICU and none of the newborns had any complication like neonatal hypoglycemia, hyperbilirubinemia, asphyxia and early neonatal death. Conclusion: DM was associated with higher maternal age, gravidity and parity as compared to normal pregnant women. This may be explained by the fact that women with diabetes are older and hence have higher gravidity and parity. In pregnant women with type 2 DM, women who were on insulin and metformin –1/80 (1.25%) had the best results on new born on their birth weight followed by Insulin 3/80 (3.75%), followed by medical nutrition therapy followed by metformin. Which was statistically significant difference in the distribution of birth weight (AGA/SGA/LGA) in cases according to treatment modality which means medical therapy alone shoul