DOI: 10.36347/sjams.2019.v07i09.057

Pages: 3200-3204

Background: Ketamine is one of the commonly used inducing agents for short surgical procedures particularly in paediatric patients. Emergence reactions and vomiting caused by ketamine are opposed by the hypnotic and antiemetic properties of propofol while ketamine provides analgesia and combat the hypotension during propofol sedation. Objective: To find out the effects of ketaminepropofol and ketamine-dexmedetomidine combinations on hemodynamic parameters and recovery time in paediatric patients undergoing minor procedures. Methodology: A prospective, randomized, controlled study was undertaken in a large tertiary hospital (Fortis Escorts Cardiac Hospital, Khulna) from January 2017 to December 2017. Informed written consent was taken from all the patients’ guardians before the procedure. The patients were randomly assigned into two groups: DK and PK with 50 patients in each group by using sealed envelope method. All patients between the age group of 1 month to 10 years of either sex undergoing cardiac catheterization lab procedures were included in the study. Results: Mean pulse rate, Mean MAP and Mean oxygen saturation were not statistically significant (p>0.05) between two groups. Tachycardia, bradycardia, hypertension and hypotension were not statistically significant (p>0.05) between two groups. Mean recovery time was found 39.6±7.9 minute in DK group and 22.3±3.5 minute in PK group. The difference was statistically significant (p<0.05) between two groups. Thirty five 35(70.0%) patients were Ketamine boluses consumption in DK group and 45(90.0%) in PK group. The difference was statistically significant (p<0.05) between two groups. Conclusion: This study observed that the no significant difference were found ketamine and propofol versus ketamine and dexmedetomidine combinations on hemodynamic stability, respiratory variables and recovery time in children undergoing minor procedures in cardiac catheterization laboratory.......................