DOI: 10.36347/sjams.2019.v07i10.001

Pages: 3225-3230

Chronic kidney disease is characterized by permanent decline of renal function that steadily proceeds to End Stage Renal Disease (ESRD). CKD is a major public health problem worldwide. Incidence rate reported is 12.0 pmarp (per million of the age related population) in children 1-18 years’ age group. Causes of CKD differ in children from that reported in adult patients. Children are particularly vulnerable to the complications of CKD. Main objective of present study was to determine the clinical characteristics, etiology and complications in children age 1-18 years with chronic kidney disease (CKD) in pre-dialytic stage. It was an observational study of 100 children who presented to us with CKD in Pediatric nephrology division of SMS Medical college Jaipur. Schwartz formula was applied to calculate the Glomerular Filtration Rate (GFR). M:F ratio was 1.7:1. Mean age of presentation was 4.36 yrs. The stage 5 was the most common presentation. Hypoplastic kidney/Dysplastic kidney was the most common cause of CKD. Anemia was the most common complication followed by hypertension and failure to thrive. The presence of CKD complications generally increased with the worsening stage of CKD. The study reveals the characteristics, etiologies and complications of chronic kidney disease to help in early detection, and create awareness about complications.