DOI: 10.36347/sjams.2019.v07i10.007

Pages: 3266-3270

Carcinoma of gall bladder is uncommon malignancy having high mortality and low five year survival rates. Gallbladder carcinoma (GBC) is the commonest cancer of the biliary tree and the most frequent cause of death from biliary malignancies. The incidence of GBC shows prominent geographic, age, race, and gender-related differences and is higher in patients with gallstones. This prompted us to study the clinicopathological aspects of the disease and the incidence of gallstones in gallbladder carcinoma patients. In this, combined retrospective (January 2009 to April 2013) and prospective ( May 2013 to December 2015) study of six years, 80 patients of gallbladder carcinoma (14 males and 66 females), (range 22-79 years; mean 48 years) were studied. Most of the patients presented with abdominal pain and mass, with jaundice. Gallstones were present in 86% of patients. Adenocarcinoma (72 %) was the commonest histological type. The study indicates that GBC is common in our scenario. It is a disease of females, has a strong association with gallstones and every cholecystectomy specimen should be examined histopathologically.