An International Publisher for Academic and Scientific Journals
Author Login 
Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 10
Lymph Node Ratio & Capsule Penetration as Independent Risk Factors In Oral Cavity Squamous Cell Carcinoma: An Institution Based Analysis
Yadav Dinesh, Goyal Sumit, Yadav Ajay
Published: Oct. 24, 2019 | 79 57
DOI: 10.36347/sjams.2019.v07i10.019
Pages: 3316-3320
Downloads
Abstract
Knowledge of independent prognos¬tic factors in patients with oral caity squamous cell carcinoma is important for appropriate treatment decisions. Given the availability of aggressive therapeutic options with known side effects and burdens for the patient, choosing the correct treatment option is vital. Using a retrospective database of pa¬tients treated over a 1year period, independent prognostic factors for disease-free survival and overall sur¬vival were assessed. Univariate anal¬ysis was used to identify significant variables, and multivariate Cox regres¬sion analysis was used to determine independent prognostic factors. 200 patients with head and neck squamous cell carcino¬mas were analysed to identify prognos¬tic factors for disease-free survival and overall survival. Although univariate analysis identified several significant factors, multivariate Cox regression analysis showed that capsule pene¬tration and lymph node ratio were the only significant factors for disease-free survival and overall survival. Lymph node ratio is an independent predictor of survival and should be examined in every patient undergoing neck dissection.