DOI: 10.36347/sjams.2019.v07i10.020

Pages: 3321-3325

Background: The diagnosis of extra pulmonary TB (EPTB) like tubercular lymphadenitis is challenging due to the paucibacillary nature of the disease. Recently, WHO recommends Gene Xpert/ CBNAAT to diagnose the patient suspected EPTB. The aims and objectives of this study to detect the sensitivity of CBNAAT over FNAC to diagnose a TB lymph node. Material and Method: This is a descriptive observational study carried out over a period of 12 months (July 2018 to June 2019) in Dept. of Pathology, CNMCH, Kolkata. All cases suspecting TB lymphadenitis between the age group of <1yr to 60yrs were included in the study. FNAC was done and material sent for Leishman Giemsa stain, ZN stain, HE and CBNAAT. Result: Total no. of cases 289. Majority of aspirates are from cervical lymph node- 94.1% (272/289). Total cytomorphological positive 50.5% cases out of total 289 cases, that is 88.48% out of total true TB cases and CBNAAT positive 94%.CBNAAT has detected more than 11.5% (19) cases which were not detected by FNAC. Conclusion: FNAC still remains the cheapest test to diagnose Lymph node TB. In cases with Granulomatous Lymphadenitis and purulent Aspirate, CBNAAT has an important role in diagnosing Lymph Node TB over FNAC.