DOI: 10.36347/sjams.2019.v07i10.045

Pages: 3448-3450

Background: Kidneys are one of the major organs of the human body that serve several essential functions. Nephrectomy is a common surgical procedure and is performed in patients with a wide range of clinical conditions ranging from symptomatic chronic infections, obstruction, calcular disease, severe traumatic injury and malignant pathologies like renal cell carcinomas and transitional cell carcinoma. Kidneys with end stage renal disease may give rise to major complications such as massive bleeding for which nephrectomy may be indicated. Radical or partial nephrectomy is the treatment of choice for a significant proportion of patients with renal tumours. Aim/Objectives: To assess the patterns and morphology of lesions in nephrectomy specimens in the hospital. Material and Methods: This retrospective study carried out in the Department of Pathology in Government Medical College, Jammu. A total of seventy nephrectomy specimens received during the period were included in the study. Paraffin blocks and slides along with case records were retrieved and studied. Results: Majority of cases were seen in 5th decade of life with a male predominance (M:F 1.7:1). Out of 70 cases, 14 were neoplastic and 56 were non-neoplastic. Out of the 14 neoplastic cases, Renal cell carcinoma was commonest (7 cases) followed by wilms tumour (4 cases) and angiomyolipoma (2 cases). Of the non-neoplastic cases, chronic pyelonephritis with hydronephrosis was seen in 42 cases, chronic pyelonephritis in 7 cases, xanthogranulomatous pyelonephritis in 5 cases and tuberculosis and traumatic kidney (1 case each). Conclusions: The study provides a fair insight into the histological patterns of lesions in nephrectomy specimens at our institution.....................