DOI: 10.36347/sjams.2019.v07i12.005

Pages: 3856-3857

Objective and AIM: Approximately 1% of pregnancy is comes under Ectopic pregnancy (EP) and pregnant women who is suffering from EP may seriously compromise their health. The main objective of this observational trial was to evaluate efficacy of methotrexate single dose for medical treatment of ectopic pregnancy. Method and Material: 80 patients treated with MTX therapy (single dose protocol 50 mg/kg, Intra muscularly) who were with ectopic pregnancy for this observational study conducted in a tertiary care teaching hospital at Katihar, Bihar. On the 4th day of MTX administration decline of plasma human chorionic gonadotropin < 15%, need to additional dose of MTX, mean of primary β-hCG level, presence of free fluid in culdesac, mean of gestational and maternal age, length of hospitalization and mean of ectopic mass size was evaluated. SPSS software version 13 were used to analyse the data. Result: 62% was the success rate, 535.49±618.36 MIU/ml was mean of primary β-hCG level, 22.89% of total patients were need to additional dose, 22.1% was needed further surgery, in 24% of patients free fluid was observed, 6.38% days were mean hospitalization days, 29.32 years was the mean of maternal age, 8.36±1.78 weeks was mean of gestational age and 2.39±0.84 cm was the mean of ectopic mass size.