DOI: 10.36347/sjams.2019.v07i12.006

Pages: 3858-3860

Objective and AIM: Many changes in coagulation profile associated with Normal pregnancy. For thromboembolism during pregnancy and labour these changes are important for intrapartum blood loss. The present study aimed at to find out in early and later part of third trimester the quantitative change in coagulation profile. Method: This prospective observational study was done among 70 cases of pregnant women in third trimester at katihar Medical College and Hospital at Katihar in Bihar District. Among which 41 cases are in 29th to 34th wks and 29 cases are within 35th to 39th wks of gestation. 70 ages matched healthy child bearing age group female were taken as control. Coagulation time, bleeding time and platelet count were done in each control and cases. Result: At 29th to 34th wks the mean platelet count in pregnancy was more than that of non-pregnant but at 35th to 39th wks the value was less in pregnancy. Similarly in third trimester than the non-pregnant mean bleeding time and coagulation time were also increases. But in 35th to 39th both the values are decreases than the 29th to 34th wks. In later part of pregnancy women platelet count was progressively decreased compared to non-pregnant women. Conclusion: Bleeding disorder and thromboembolism are two major complications of pregnancy. Proper study of coagulation profile is necessary to prevent the complication.