An International Publisher for Academic and Scientific Journals
Author Login 
Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 03
Clinical and Neuroimaging Profile of Ring Enhancing Lesions in Children Presenting to Department of Pediatrics, Government General Hospital, Kakinada
Dr. P. Deepa, Dr. D. Manikyamba, Dr. K. Amulya, Dr. E.S. Sailaja, Dr. G. Poornima
Published: March 30, 2019 | 92 70
DOI: 10.36347/sjams.2019.v07i03.018
Pages: 945-949
Downloads
Abstract
Ring enhancing lesions are one of the most commonly encountered neuroimaging abnormalities in patients presenting with acute seizures in tropical countries. A variety of infective and noninfective processes display a pattern of ring enhancement on neuroimaging, which often prohibits a reliable diagnosis and clinical correlation is essential. Various causes of ring enhancing lesions are neurocysticercosis, tuberculoma, pyogenic abscess, toxoplasmosis, cavernous angioma, primary or metastatic tumours of brain. Aim is to study the various clinical presentations of ring enhancing lesion, etiology, distribution and size of ring enhancing lesions and their outcome. This is a prospective observational study done over 18 month’s i.e, from January 2012 to June 2013, in the department of pediatrics, Government general hospital, Kakinada. A total of 74 children less than 14 years of age with ring enhancing lesion in neuroimaging are enrolled in the study. Neurocysticercosis was diagnosed based on Del Brutto diagnostic criteria. Most common cause of ring enhancing lesion was Neurocysticercosis (70.27%) followed by Tuberculoma (27.7%).Most common clinical manifestation was seizure (91%). Partial seizures were more commonly seen than generalised seizures. No gender difference was seen in the prevalence of Neurocysticercosis and Tuberculoma. Both Neurocysticercosis and Tuberculoma were common in children above 5years of age (90%).Single ring enhancing lesion was common, both in Neurocysticercosis and Tuberculoma. Larger lesions were more commonly associated with Tuberculoma. Response to therapy was similar both in children who were given 8 day Albendazole therapy versus 28 day Albendazole therapy.