DOI: 10.36347/sjams.2019.v07i03.046

Pages: 1093-1096

Background and Objectives: Blood stream infection is very critical infection and Blood culture is very essential investigation in such patient in tertiary care hospital. Study of different bacterial isolates from blood stream infection and its antibiotic sensitivity pattern is very useful guide to clinicians for starting empirical treatment. Methods: The study was carried out from Jan 2017 to April 2017 in Microbiology dept. at Sir T Hospital Bhavnagar. Total 1575 samples of blood were cultured by conventional methods and antibiotic susceptibility testing was done by Kirby Bauer disc diffusion method as per CLSI guidelines. Result: Out of 1575 blood samples, 351 (22.29%) were positive for bacterial culture, Amongst Gram negative bacteria most common isolates were E. coli 39(11.11%) and Klebsiella spp. 39(11.11%). Amongst Gram positive bacteria most common isolates were Staphylococcus aureus 68(19.37%) and CoNS 148(42.17%). These isolates were sensitive to Gentamycin, Vancomycin, Linezolid, Meropenam and Piperacillin-Tazobactum. Conclusion: Most common bacterial isolates from blood stream infection were S. aureus, CoNS, E. coli and Klebsiella spp. The antibiotics that helpful to treat these infections are Gentamycin, Vancomycin, Meropenam and Piperacillin-Tazobactum.