DOI: 10.36347/sjams.2019.v07i03.053

Pages: 1129-1137

Background: Brain tumours comprise of heterogeneous group of benign and malignant tumours. Tumours of Central Nervous System are considered to be among the most notorious of all tumours. The present study helped in diagnosis of number of Central Nervous System tumour cases, their prognosis and further management depending on their grading. Aims and objectives: Aim of present study was to diagnose and classify tumours of Central Nervous System based on morphological features of WHO Classification of Central Nervous System tumours- 2007 and 2016 and to correlate histopathological findings with imaging studies and clinical details. Material and methods: Present study was a two years prospective study of 52 CNS tumours received in a tertiary care hospital from June 2016 to May 2018. Specimens were received in the form of biopsy and histopathological study was done. Detail records including clinical history and radiological findings were noted. Results: Out of 52 cases, maximum number of cases (n=19) were meningioma, followed by astrocytoma 15 cases. While choroid plexus papilloma was least in number i.e. 1 case. Maximum number of cases were in the age group of 51-60 years (26.92%) followed by 61-70 years age group (21.15%). Headache, giddiness and vomiting were the most common clinical presentation. Meningioma and schwannoma presented as slow growing tumours. Conclusion: Meningioma and astrocytoma form the majority of CNS tumors. There are limitations in making definitive diagnosis of CNS tumors with clinical examination and radiological investigations. Histopathological examination is the gold standard for making definitive diagnosis of CNS tumours which helps in further management.