DOI: 10.36347/sjams.2019.v07i03.055

Pages: 1144-1148

Nausea and vomiting are common side effects in parturients undergoing caesarean delivery performed underspinal anaesthesia can be very unpleasant to the patients. The aim of the present study was to compare the efficacy and safety using intravenous metoclopramide and midazolam for the prevention of nausea¬ vomiting in parturient undergoing cesarean section under spinal anesthesia. This prospective and randomized double blind study was conducted in 100 parturient aged between 21 and 40 years, ASA physical status É, scheduled to undergo elective cesarean section under spinal anesthesia. Parturient presenting for cesarean section with standardized 0.5% hyperbaric bupivacaine 2 ml spinal anesthesia were randomized to intravenous metoclopramide 10 mg (group I) or intrathecal midazolam 2mg ( group II). The nausea, retching and vomiting were observed in 12%, 10%&4% patients in midazolam group, 52%, 20%& 2% patients of metoclopromide groups. Hypotension was observed in both groups, but respiratory failure was observed in 38% patients of midazlam group, but not found in metaclopromide group. Both drugs were effective in controlling the peri operative nausea and vomiting in this study.